Anaphylaxis Action Plan
For patients who have a suspected or confirmed IgE-mediated food allergy, it is important to provide the family with an anaphylaxis action plan. An action plan provides families and caregivers with information on common signs and symptoms of an allergic reaction and when to give epinephrine.
We suggest using the American Academy of Pediatrics (AAP) anaphylaxis action plan. For current information from the AAP on how to fill out an action plan and current action plan, see Guidance on Completing a Written Allergy and Anaphylaxis Emergency Plan.
Anaphylaxis in infants and toddlers can look different than in older children and adults. Additionally, infants are unable to verbalize their symptoms, so it is important that parents and caregivers can recognize signs that may be indicative of an allergic reaction. We have included below a breakdown of the symptoms included and how they may present differently in infants and toddlers, as well as important take home points for discussing with families.
Important take home points for families:
- When in doubt, give epinephrine!
- Infants and toddlers having an allergic reaction may look different than older children or adults experiencing anaphylaxis because these younger children cannot dictate how they are feeling.
- Look for new, abnormal changes in the child’s appearance and/or behavior.
- If more than one body system is involved, administer epinephrine.
Understanding and Explaining Severe Symptoms:
Symptoms | Infant/Toddler Specific Terms | Lay-Terms | Discussion points for parents/caregivers |
---|---|---|---|
“Shortness of breath, wheezing, or coughing” | Nasal flaring Grunting Exaggerated abdominal breathing Retractions (suprasternal and intercostal) Tripoding Wheezing Coughing | Widening of the nostrils to allow greater airflow Low-pitched groan indicating distress or difficulty breathing Larger than normal expansion of the infant’s tummy when breathing in Sucking in of skin around the chest and ribs Child leans forward with arched back and hands on legs, a position that allows increased airflow High-pitched squeaking sound when breathing in and/or out | Signs of shortness of breath in the infant/toddler, in layperson terms Identification of new or abnormal sounds and behaviors in the infant/toddler that may indicate difficulty breathing |
“Skin color is pale or has a bluish color” | Perioral cyanosis Cyanosis of nailbeds/ Delayed capillary refill Mottling Pallor | Blueish color of/around the lips White/blue fingertips with slow (>3 seconds) return of pink color to nailbeds after pressure is applied Red, lacy, speckled appearance of the skin, particularly the arms and legs Pale/white appearance of the face | Identification of new or abnormal skin color in the infant/toddler Cyanosis identification |
“Weak pulse; Fainting or dizziness” | Loss of consciousness Lethargy Sudden/abnormal onset of cold hands and feet | Child becomes unresponsive/passes out Child is very slow moving and takes longer than usual to respond to you; seems “out of it” Hands and/or feet feel very cold (typically accompanied by white/blue coloring) | Signs of cardiovascular compromise in the infant/toddler, in layperson terms Limited value of hypotension assessment in early anaphylaxis, with heart rate detection important for the healthcare provider |
“Tight or hoarse throat; Trouble breathing or swallowing” | Change in pitch/tone of voice and cry Stridor Snoring Nasal congestion Excessive drooling/ protrusion of tongue Wheezing, grunting, nasal flaring | Sound of voice/ cry is different/ strained/ raspy High pitched crowing sound when breathing in Sound as if the infant is snoring when breathing in More drooling than normal with the infant repetitively sticking tongue out Sounds indicating trouble breathing as previously described | Signs the infant/toddler may be experiencing throat constriction or trouble breathing or swallowing, in layperson terms |
“Swelling of lips or tongue that bother breathing” | Bilateral lip swelling with difficulty breathing Swelling that is expanding Tongue obstructing airway Inability to visualize posterior pharynx Air hunger | Both lips are noticeably larger than usual Lips/mouth is puffy and keeps getting bigger Tongue is noticeably larger than usual and taking up most of the room in the mouth You cannot see the back of the throat with the child’s mouth wide open Child sounds like he/she is choking or gasping for air | Signs of compromised breathing that warrant epinephrine administration, in layperson terms How the extent of swelling may correlate with level of concern for true anaphylactic reaction |
“Vomiting or diarrhea (that is severe or combined with other symptoms)” | Persistent vomiting Vomiting resulting in dehydration Vomiting uncharacteristic for the child Vomiting similar to that of previous allergic reaction | Vomiting that doesn’t stop once the child eats the food Vomiting so much that the child appears dehydrated (sunken eyes; flat, sunken fontanelle (soft spot on top of infant’s head); vomiting bile/ liquid after clearing food from stomach) -Vomiting that is different from the child’s usual “spit up” or vomiting Vomiting like the last time the child had an allergic reaction | Vomiting/diarrhea characteristics likely associated with anaphylaxis Identification of new or abnormal vomiting/diarrhea in the infant/toddler |
“Many hives or redness over body” | Hives spreading to trunk Hives in areas of the body not in contact with the food | Round, raised, red blotches on the child’s chest, stomach, and/or back Round, raised, red blotches on the skin that the food did not touch | Significance of localized vs. full body hives in context of contact vs. systemic reactions |
“Feeling of ‘doom’, confusion, altered consciousness, or agitation” | Excessive crying Increased irritability Lethargic Inconsolable | Crying relentlessly Abnormally angry, having a temper tantrum Abnormally sleepy or slow moving -Cannot be calmed or consoled by ways of soothing that usually work | Such ominous or ambiguous signs in the infant/ toddler that may be indicative of anaphylaxis, in layperson terms |
For Mild to Moderate Symptoms:
These symptoms may be the first signs of anaphylaxis. Therefore, it is important the child is monitored for progression of mild to severe symptoms. If the child has any of these symptoms in addition to any symptoms described previously, epinephrine should be administered. If the infant or toddler has symptoms that involve two or more body symptoms, epinephrine administration is warranted. Caution caregivers that change in behavior is only relevant if attributable to an allergic reaction.
Understanding and explaining mild and moderate symptoms:
Symptoms | Infant/ Toddler Specific Terms | Lay-Terms | Discussion points for parents/caregivers |
---|---|---|---|
“Itchy nose, sneezing, itchy mouth” | Nasal/perioral itching Repetitive protrusion of tongue Appearing in distress | Child scratching or rubbing nose and/or mouth Child keeps sticking out tongue as if he/she has a bad taste in the mouth Signs of discomfort as described previously, such as inconsolable crying, irritability/ agitation, appearing uncomfortable | Signs of itchy nose/mouth, in layperson terms Identification of new or abnormal signs of irritation in the infant/toddler |
“A few hives” | Progressive vs. localized hives Contact hives | Round, raised, red blotches that do not spread and appear in one area Round, raised, red blotches only on the area(s) of skin that the food touched | Description of appearance of hives Possibility for hive progression over time and need for monitoring of infant/toddler Reiteration of significance of localized vs. widely-distributed hive development |
“Mild stomach nausea or discomfort” | Borborygmi Gagging, retching, dry heaving Excessive crying or irritability | Hiccup-like sounds with sucking in of stomach; gagging without vomiting Child will not stop crying and you cannot see any visible injury or sign of discomfort | Signs of nausea or stomach upset in the infant/toddler, in layperson terms |
References
- Wang, J., & Sicherer, S. H. (2017). Guidance on completing a written allergy and anaphylaxis emergency plan. Pediatrics, 139(3).
- Dosanjh, A. (2013). Infant anaphylaxis: The importance of early recognition. Journal of Asthma and Allergy, 6, 103-107.
- Greenhawt, M., Gupta, R. S., Meadows, J. A., Pistiner, M., Spergel, J. M., Camargo, C. A., Simons, F. E. R., & Lieberman, P. L. (2019). Guiding principles for the recognition, diagnosis, and management of infants with anaphylaxis: An expert panel consensus. Journal of Allergy and Clinical Immunology, 7(4), 1148-1156.